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The Arthur of the Iberians
Up-to-date Coverage of the scope and extent of the important tradition of Arthurian material in Iberian languages and of the modern scholarship on it. (= Wide-ranging bibliographical coverage and guide to both texts and research on them.) Written by Specialists in the different Romance languages of the Iberian Peninsula (Portuguese, Catalan, Galician, Spanish and its dialects). (= Expert analysis of different traditions by leading scholars from Spain and the UK.) Wide-ranging Study not only of medieval and Renaissance literary texts, but also of modern Arthurian fiction, of the global spread of Arthurian legends in the Spanish and Portuguese worlds, and of the social impact of the legends through adoption of names of Arthurian characters and imitation of practices narrated in the legends. (=A comprehensive guide to both literary and social impact of Arthurian material in major world languages.)
Ingrid Calame
The Fruitmarket Gallery is proud to present the first solo exhibition in Scotland of the work of American artist Ingrid Calame, whose beautifully-coloured, intricate drawings and paintings have a specific, if abstracted relationship to the world. Calame's paintings and drawings all begin with the artist tracing marks, stains and cracks on the ground. Back in the studio, the tracings are combined, layered and re-traced in coloured pencil, and painted in enamel or, more recently oil paint. The paintings and drawings that result from this singular process are beautiful and intelligent abstract works. Displayed in a gallery, they retain their connection with the world outside at several removes, exerting an oddly insistent presence.
Melatonin, Neuroprotective Agents and Antidepressant Therapy
This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms,...
History of Psychopharmacology. the Origins of Scientificmedicine: Biological Pillars on the Birth of Psychopharmacology.
In recent years, with the introduction of new molecules into the arsenal of psychiatric therapy, the historical significance of classical psychotropic drugs to modern society has been lost. Keep in mind that its modern history is very short, born in the 1950s with the introduction of lithium, chlorpromazine, and imipramine, known as the "revolution of psychopharmacology." The purpose of this work it to review how psychoactive substances have been discovered, developed, and applied over the millennia. The text presents the drugs that are used in medicine, their origins, the principles of biological theories of mental disorders, and contribution of basic research.
Melatonin
There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases and other ailments. Topics include: The basic aspects of melatonin’s physiology, including its production, bioavailability, and metabolism The functional importance of melatonin receptors and their role in mediating the therapeutic effectiveness of melatonin in cancer Melatonin’s effect on the regulation of blood pressure, sleep, ...
Attention Deficit Hyperactivity Disorder (ADHD)
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with underlying brain anatomical and functional measures, as well as familial/genetic factors that are major foci of neuropsychiatric research. In recent years, ADHD is one of the neuropsychiatric diseases receiving more attention in scientific literature. During this decade, numerous studies were published on the implementation of diagnostic criteria and assessment tools for clinical research and the social impact of the disease, which continued to discuss genetic and neurobiological aspects. Psychostimulants are highly effective medications for the treatment of ADHD, and the development of long-acting s...
Melatonin and Melatonergic Drugs in Clinical Practice
The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinson’s disease, Alzheimer’s disease. Additionally, melatonin’s therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonin’s antioxidant role...
Neurobiology of Depression
Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, mol
